The Boysrecently announced appearances by Jared Padalecki and Misha Collins in its upcoming fifth season, reuniting the two actors with formerSupernaturalco-star Jensen Ackles and Eric Kripke, the creator of both shows. TheSupernaturalcast members had hoped toreunite for a revival in 2025 (according to Jared Padalecki), and while the reunion might be happening as different characters on a different show, they’ve made the wish for a 2025 reunion come true.
Over the course of the first four seasons,otherSupernaturalactors have shown up onThe Boys, both as major and minor characters, butthis will be Padalecki and Collins' first time on the show. Padalecki has confirmed that he will begin filming at the end of March, though not much else is known at this point. EvenThe Boyscast is being kept in the dark about season 5’s ending, so whether we get more information about the upcoming season and itsSupernaturalreunion remains to be seen.

Jensen Ackles & Jared Padalecki WILL Interact In The Boys Season 5
The Winchester Brothers' Actors Will Reunite On Screen Together
When Jared Padalecki first announced his involvement, the lack of further information meant that it was unclear even whether his character and Jensen Ackles' would interact.Business Insiderhas confirmed thatPadalecki will interact with Ackles on screen, though the former doesn’t yet know any further information. He’s still not even sure what his character will entail, as he explained, “I don’t know if we like, bump into each other. I don’t know much about it” (Business Insider).
While Waiting For The Boys Season 5, Watch Prime Video’s Other Anti-Superhero Show Streaming Season 3 Now
The highly anticipated fifth season of The Boys is still a long way away, but while waiting for new episodes, fans can watch a similar series.
It would have been disappointing if this casting happened and Padalecki and Ackles didn’t have the chance to reunite on screen, but that’s not the extent what this reunion needs to faciliate. Padalecki and Ackles spent 15 seasons portraying brothers together in a show centered on family and brotherhood, andnot taking advantage of their on-screen chemistry would be wasted potential. Hopefully,Jared Padalecki’s scenes with Jensen Ackles in season 5last long enough for fans to feel satisfied.

Ackles & Padalecki’s Reunion In The Boys Won’t Be Complete Without Misha Collins
Misha Collins Has Also Been Confirmed To Have Scenes With Jensen Ackles
Misha Collins hasn’t said as much about his involvement as Jared Padalecki, but arepresentative ofThe Boysconfirmed thatCollins will also have scenes with Ackles. We still don’t know if Padalecki and Collins will appear on-screen together, let alone if they’ll appear in the same episode. However, knowing that both Padalecki and Collins will have scenes with Jensen Ackles brings us one step closer to a full-blown reunion, and it’s good to know that both guest stars will get to interact with their former castmate who plays a major role inThe Boys.
Knowing that both Padalecki and Collins will have scenes with Jensen Ackles brings us one step closer to a full-blown reunion.
While we’re still waiting for further information beyondCollins' and Padalecki’sThe Boyscastingand shared scenes with Ackles, it’s exciting to know that they’ll be on a show together again, no matter how long it lasts. Just like Sam and Dean, Castiel helped makeSupernaturalwhat it is, and theSupernaturalreunion inThe Boysneeds all three actors to feel complete.